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Mechanisms of mutational robustness in transcriptional regulation
Robustness is the invariance of a phenotype in the face of environmental or genetic change. The phenotypes produced by transcriptional regulatory circuits are gene expression patterns that are to some extent robust to mutations. Here we review several causes of this robustness. They include robustne...
Autores principales: | Payne, Joshua L., Wagner, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621482/ https://www.ncbi.nlm.nih.gov/pubmed/26579194 http://dx.doi.org/10.3389/fgene.2015.00322 |
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