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Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca(2+)

Polycystic kidney disease (PKD) protein 2 Like 1 (PKD2L1), also called transient receptor potential polycystin-3 (TRPP3), regulates Ca(2+)-dependent hedgehog signalling in primary cilia, intestinal development and sour tasting but with an unclear mechanism. PKD2L1 is a Ca(2+)-permeable cation channe...

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Detalles Bibliográficos
Autores principales: Hussein, Shaimaa, Zheng, Wang, Dyte, Chris, Wang, Qian, Yang, JungWoo, Zhang, Fan, Tang, Jingfeng, Cao, Ying, Chen, Xing-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621500/
https://www.ncbi.nlm.nih.gov/pubmed/26502994
http://dx.doi.org/10.1038/srep15752