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Emergent Stem Cell Homeostasis in the C. elegans Germline Is Revealed by Hybrid Modeling

The establishment of homeostasis among cell growth, differentiation, and apoptosis is of key importance for organogenesis. Stem cells respond to temporally and spatially regulated signals by switching from mitotic proliferation to asymmetric cell division and differentiation. Executable computer mod...

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Detalles Bibliográficos
Autores principales: Hall, Benjamin A., Piterman, Nir, Hajnal, Alex, Fisher, Jasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621618/
https://www.ncbi.nlm.nih.gov/pubmed/26200879
http://dx.doi.org/10.1016/j.bpj.2015.06.007