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Phenolic alkaloids from Menispermum dauricum inhibits BxPC-3 pancreatic cancer cells by blocking of Hedgehog signaling pathway

BACKGROUND: The Hedgehog (Hh) signaling pathway plays an important role in pancreatic cancer (PC) cells. Phenolic alkaloids from Menispermum dauricum (PAMD), a traditional Chinese medicine used for the treatment of immune disorders, have been reported to have antitumor activity recently. OBJECTIVE:...

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Detalles Bibliográficos
Autores principales: Zhou, Zhong-guang, Zhang, Chao-ying, Fei, Hong-xin, Zhong, Li-li, Bai, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621636/
https://www.ncbi.nlm.nih.gov/pubmed/26600712
http://dx.doi.org/10.4103/0973-1296.165548