Bimodal regulation of an Elk subfamily K(+) channel by phosphatidylinositol 4,5-bisphosphate

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) regulates Shaker K(+) channels and voltage-gated Ca(2+) channels in a bimodal fashion by inhibiting voltage activation while stabilizing open channels. Bimodal regulation is conserved in hyperpolarization-activated cyclic nucleotide–gated (HCN) channels...

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Detalles Bibliográficos
Autores principales: Li, Xiaofan, Anishkin, Andriy, Liu, Hansi, van Rossum, Damian B., Chintapalli, Sree V., Sassic, Jessica K., Gallegos, David, Pivaroff-Ward, Kendra, Jegla, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621751/
https://www.ncbi.nlm.nih.gov/pubmed/26503718
http://dx.doi.org/10.1085/jgp.201511491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621751/
https://www.ncbi.nlm.nih.gov/pubmed/26503718
http://dx.doi.org/10.1085/jgp.201511491

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