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Sleep disruption impairs hematopoietic stem cell transplantation in mice

Many of the factors affecting the success of hematopoietic cell transplantation are still unknown. Here we show in mice that donor’s sleep deprivation reduces the ability of its hematopoietic stem cells (HSCs) to engraft and reconstitute the blood and bone marrow of an irradiated recipient by more t...

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Detalles Bibliográficos
Autores principales: Rolls, Asya, Pang, Wendy W., Ibarra, Ingrid, Colas, Damien, Bonnavion, Patricia, Korin, Ben, Heller, H. Craig, Weissman, Irving L., de Lecea, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621781/
https://www.ncbi.nlm.nih.gov/pubmed/26465715
http://dx.doi.org/10.1038/ncomms9516