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NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin

The proliferation of normal cells is inhibited at confluence, but the molecular basis of this phenomenon, known as contact-dependent inhibition of proliferation, is unclear. We previously identified the neurofibromatosis type 2 (NF2) tumor suppressor Merlin as a critical mediator of contact-dependen...

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Detalles Bibliográficos
Autores principales: Chiasson-MacKenzie, Christine, Morris, Zachary S., Baca, Quentin, Morris, Brett, Coker, Joanna K., Mirchev, Rossen, Jensen, Anne E., Carey, Thomas, Stott, Shannon L., Golan, David E., McClatchey, Andrea I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621825/
https://www.ncbi.nlm.nih.gov/pubmed/26483553
http://dx.doi.org/10.1083/jcb.201503081