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NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin
The proliferation of normal cells is inhibited at confluence, but the molecular basis of this phenomenon, known as contact-dependent inhibition of proliferation, is unclear. We previously identified the neurofibromatosis type 2 (NF2) tumor suppressor Merlin as a critical mediator of contact-dependen...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621825/ https://www.ncbi.nlm.nih.gov/pubmed/26483553 http://dx.doi.org/10.1083/jcb.201503081 |