A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia

Lethal giant larvae (Lgl) plays essential and conserved functions in regulating both cell polarity and tumorigenesis in Drosophila melanogaster and vertebrates. It is well recognized that plasma membrane (PM) or cell cortex localization is crucial for Lgl function in vivo, but its membrane-targeting...

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Detalles Bibliográficos
Autores principales: Dong, Wei, Zhang, Xuejing, Liu, Weijie, Chen, Yi-jiun, Huang, Juan, Austin, Erin, Celotto, Alicia M., Jiang, Wendy Z., Palladino, Michael J., Jiang, Yu, Hammond, Gerald R.V., Hong, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621827/
https://www.ncbi.nlm.nih.gov/pubmed/26483556
http://dx.doi.org/10.1083/jcb.201503067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621827/
https://www.ncbi.nlm.nih.gov/pubmed/26483556
http://dx.doi.org/10.1083/jcb.201503067

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