The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition

Cortically anchored dynein orients the spindle through interactions with astral microtubules. In budding yeast, dynein is offloaded to Num1 receptors from microtubule plus ends. Rather than walking toward minus ends, dynein remains associated with plus ends due in part to its association with Pac1/L...

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Detalles Bibliográficos
Autores principales: Lammers, Lindsay G., Markus, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621840/
https://www.ncbi.nlm.nih.gov/pubmed/26483554
http://dx.doi.org/10.1083/jcb.201506119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621840/
https://www.ncbi.nlm.nih.gov/pubmed/26483554
http://dx.doi.org/10.1083/jcb.201506119

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