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ERO1-independent production of H(2)O(2) within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding
The endoplasmic reticulum (ER)–localized peroxiredoxin 4 (PRDX4) supports disulfide bond formation in eukaryotic cells lacking endoplasmic reticulum oxidase 1 (ERO1). The source of peroxide that fuels PRDX4-mediated disulfide bond formation has remained a mystery, because ERO1 is believed to be a ma...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621842/ https://www.ncbi.nlm.nih.gov/pubmed/26504166 http://dx.doi.org/10.1083/jcb.201506123 |