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Efficient self-assembly and protective efficacy of infectious bursal disease virus-like particles by a recombinant baculovirus co-expressing precursor polyprotein and VP4

BACKGROUND: Virus-like particle (VLP) technology is considered one of the most promising approaches in animal vaccines, due to the intrinsic immunogenic properties as well as high safety profile of VLPs. In this study, we developed a VLP vaccine against infectious bursal disease virus (IBDV), which...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-Jeong, Kim, Ji-Ye, Kye, Soo-jeong, Seul, Hee-Jung, Jung, Suk-Chan, Choi, Kang-Seuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621879/
https://www.ncbi.nlm.nih.gov/pubmed/26502988
http://dx.doi.org/10.1186/s12985-015-0403-4