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Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder

Although more than 90% systemic mastocytosis (SM) patients express gain of function mutations in the KIT receptor, recent next generation sequencing has revealed the presence of several additional genetic and epigenetic mutations in a subset of these patients, which confer poor prognosis and inferio...

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Detalles Bibliográficos
Autores principales: Chatterjee, Anindya, Ghosh, Joydeep, Kapur, Reuben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621888/
https://www.ncbi.nlm.nih.gov/pubmed/26158763