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Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions

Tumor growth is not solely a consequence of autonomous tumor cell properties. Rather, tumor cells act upon and are acted upon by their microenvironment. It is tumor tissue biology that ultimately determines tumor growth. Thus, we developed a compound library screen for agents that could block essent...

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Detalles Bibliográficos
Autores principales: Sengupta, Rajarshi, Barone, Amy, Marasa, Jayne, Taylor, Sara, Jackson, Erin, Warrington, Nicole M., Rao, Shyam, Kim, Albert H., Leonard, Jeffrey R., Piwnica-Worms, David, Rubin, Joshua B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621891/
https://www.ncbi.nlm.nih.gov/pubmed/26286961