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Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences

Amyotrophic Lateral Sclerosis (ALS) is an invariably fatal neurodegenerative disorder, which specifically targets motor neurons in the brain, brain stem and spinal cord. Whilst the etiology of ALS remains unknown, fragmentation of the Golgi apparatus is detected in ALS patient motor neurons and in a...

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Detalles Bibliográficos
Autores principales: Sundaramoorthy, Vinod, Sultana, Jessica M., Atkin, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621950/
https://www.ncbi.nlm.nih.gov/pubmed/26578862
http://dx.doi.org/10.3389/fnins.2015.00400