Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions

Pixantrone is a novel aza-anthracenedione active against aggressive lymphoma and is being evaluated for use against various hematologic and solid tumors. The drug is an analog of mitoxantrone, but displays less cardiotoxicity than mitoxantrone or the more commonly used doxorubicin. Although pixantro...

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Detalles Bibliográficos
Autores principales: Beeharry, Neil, Di Rora, Andrea Ghelli Luserna, Smith, Mitchell R, Yen, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621998/
https://www.ncbi.nlm.nih.gov/pubmed/26177126
http://dx.doi.org/10.1080/15384047.2015.1070979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621998/
https://www.ncbi.nlm.nih.gov/pubmed/26177126
http://dx.doi.org/10.1080/15384047.2015.1070979

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