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Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions
Pixantrone is a novel aza-anthracenedione active against aggressive lymphoma and is being evaluated for use against various hematologic and solid tumors. The drug is an analog of mitoxantrone, but displays less cardiotoxicity than mitoxantrone or the more commonly used doxorubicin. Although pixantro...
Autores principales: | Beeharry, Neil, Di Rora, Andrea Ghelli Luserna, Smith, Mitchell R, Yen, Timothy J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621998/ https://www.ncbi.nlm.nih.gov/pubmed/26177126 http://dx.doi.org/10.1080/15384047.2015.1070979 |
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