rs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population

rs712 within 3′-untranslated region of KRAS can affect the specific binding between the mRNA and its targeted microRNAs, leading to the activation of KRAS oncogene. However, the possible association between the locus and susceptibility to colorectal cancer (CRC) remains unclear. We investigated geno...

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Detalles Bibliográficos
Autores principales: Jiang, Qiang-Hua, Peng, Hong-Xin, Zhang, Yi, Tian, Peng, Xi, Zu-Lian, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622418/
https://www.ncbi.nlm.nih.gov/pubmed/26543374
http://dx.doi.org/10.2147/OTT.S89746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622418/
https://www.ncbi.nlm.nih.gov/pubmed/26543374
http://dx.doi.org/10.2147/OTT.S89746

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