Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency

Berberine (BBR), an isoquinoline alkaloid mainly isolated from plants of Berberidaceae family, is extensively used to treat gastrointestinal infections in clinics. It has been reported that BBR can block human ether-a-go-go-related gene (hERG) potassium channel and inhibit its membrane expression. T...

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Detalles Bibliográficos
Autores principales: Yan, Meng, Zhang, Kaiping, Shi, Yanhui, Feng, Lifang, Lv, Lin, Li, Baoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622489/
https://www.ncbi.nlm.nih.gov/pubmed/26543354
http://dx.doi.org/10.2147/DDDT.S91561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622489/
https://www.ncbi.nlm.nih.gov/pubmed/26543354
http://dx.doi.org/10.2147/DDDT.S91561

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