Overexpression of PI3K p110α contributes to acquired resistance to MET inhibitor, in MET-amplified SNU-5 gastric xenografts

Gastric cancer is one of the most virulent malignant diseases and is the second leading cause of cancer mortality in the world. The receptor tyrosine kinase MET is constitutively activated in many gastric cancers and its expression is strictly required for survival of some gastric cancer cells. Targ...

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Detalles Bibliográficos
Autores principales: Ji, Fujian, Liu, Xuanwen, Wu, Yuanyu, Fang, Xuedong, Huang, Guomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622552/
https://www.ncbi.nlm.nih.gov/pubmed/26543351
http://dx.doi.org/10.2147/DDDT.S89410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622552/
https://www.ncbi.nlm.nih.gov/pubmed/26543351
http://dx.doi.org/10.2147/DDDT.S89410

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