Cooperative stabilization of the SIR complex provides robust epigenetic memory in a model of SIR silencing in Saccharomyces cerevisiae

How alternative chromatin-based regulatory states can be made stable and heritable in order to provide robust epigenetic memory is poorly understood. Here, we develop a stochastic model of the silencing system in Saccharomyces cerevisiae that incorporates cooperative binding of the repressive SIR co...

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Detalles Bibliográficos
Autores principales: Sneppen, Kim, Dodd, Ian B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622568/
https://www.ncbi.nlm.nih.gov/pubmed/25830651
http://dx.doi.org/10.1080/15592294.2015.1017200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622568/
https://www.ncbi.nlm.nih.gov/pubmed/25830651
http://dx.doi.org/10.1080/15592294.2015.1017200

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