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Functional inhibition of β-catenin-mediatedWnt signaling by intracellular VHHantibodies

The Wnt signaling pathway is of central importance in embryogenesis, development and adult tissue homeostasis, and dysregulation of this pathway is associated with cancer and other diseases. Despite the developmental and potential therapeutic significance of this pathway, many aspects of Wnt signali...

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Detalles Bibliográficos
Autores principales: Newnham, Laura E, Wright, Michael J, Holdsworth, Gill, Kostarelos, Kostas, Robinson, Martyn K, Rabbitts, Terence H, Lawson, Alastair D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622660/
https://www.ncbi.nlm.nih.gov/pubmed/25524068
http://dx.doi.org/10.4161/19420862.2015.989023