The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells

The receptor tyrosine kinase HER2 is known to play a central role in mitogenic signaling, motivating the development of targeted, HER2-specific therapies. However, despite the longstanding use of antibodies to target HER2, controversies remain concerning antibody/HER2 trafficking behavior in cancer...

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Detalles Bibliográficos
Autores principales: Ram, Sripad, Kim, Dongyoung, Ober, Raimund J, Ward, E Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622696/
https://www.ncbi.nlm.nih.gov/pubmed/25517306
http://dx.doi.org/10.4161/mabs.29865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622696/
https://www.ncbi.nlm.nih.gov/pubmed/25517306
http://dx.doi.org/10.4161/mabs.29865

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