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Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation
The mechanism responsible for developmental stage-specific regulation of γ-globin gene expression involves DNA methylation. Previous results have shown that the γ-globin promoter is nearly fully demethylated during fetal liver erythroid differentiation and partially demethylated during adult bone ma...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622718/ https://www.ncbi.nlm.nih.gov/pubmed/25932923 http://dx.doi.org/10.1080/15592294.2015.1039220 |