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Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

The mechanism responsible for developmental stage-specific regulation of γ-globin gene expression involves DNA methylation. Previous results have shown that the γ-globin promoter is nearly fully demethylated during fetal liver erythroid differentiation and partially demethylated during adult bone ma...

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Detalles Bibliográficos
Autores principales: Ruiz, Maria Armila, Rivers, Angela, Ibanez, Vinzon, Vaitkus, Kestis, Mahmud, Nadim, DeSimone, Joseph, Lavelle, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622718/
https://www.ncbi.nlm.nih.gov/pubmed/25932923
http://dx.doi.org/10.1080/15592294.2015.1039220