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Epigenetic heterogeneity of developmentally important genes in human sperm: Implications for assisted reproduction outcome

The molecular basis of male infertility is poorly understood, the majority of cases remaining unsolved. The association of aberrant sperm DNA methylation patterns and compromised semen parameters suggests that disturbances in male germline epigenetic reprogramming contribute to this problem. So far...

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Detalles Bibliográficos
Autores principales: Kuhtz, Juliane, Schneider, Eberhard, El Hajj, Nady, Zimmermann, Lena, Fust, Olga, Linek, Bartosz, Seufert, Rudolf, Hahn, Thomas, Schorsch, Martin, Haaf, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622742/
https://www.ncbi.nlm.nih.gov/pubmed/25625849
http://dx.doi.org/10.4161/15592294.2014.988063