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Consistency of quality attributes for the glycosylated monoclonal antibody Humira® (adalimumab)

Humira® (adalimumab) is a recombinant human IgG1 monoclonal antibody (mAb) glycoprotein consisting of 1330 amino acids that is specific for human tumor necrosis factor (TNF). The biological activity and clinical profile of mAb therapeutics, including adalimumab, is influenced by their protein struct...

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Detalles Bibliográficos
Autores principales: Tebbey, Paul W, Varga, Amy, Naill, Michael, Clewell, Jerry, Venema, Jaap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622832/
https://www.ncbi.nlm.nih.gov/pubmed/26230301
http://dx.doi.org/10.1080/19420862.2015.1073429