Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts

Diabetic foot ulcers (DFUs) are a serious complication of diabetes. Previous exposure to hyperglycemic conditions accelerates a decline in cellular function through metabolic memory despite normalization of glycemic control. Persistent, hyperglycemia-induced epigenetic patterns are considered a cent...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Lara K, Maione, Anna G, Smith, Avi, Gerami-Naini, Behzad, Iyer, Lakshmanan K, Mooney, David J, Veves, Aristidis, Garlick, Jonathan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622843/
https://www.ncbi.nlm.nih.gov/pubmed/25437049
http://dx.doi.org/10.4161/15592294.2014.967584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622843/
https://www.ncbi.nlm.nih.gov/pubmed/25437049
http://dx.doi.org/10.4161/15592294.2014.967584

Ejemplares similares