Cargando…

Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts

Diabetic foot ulcers (DFUs) are a serious complication of diabetes. Previous exposure to hyperglycemic conditions accelerates a decline in cellular function through metabolic memory despite normalization of glycemic control. Persistent, hyperglycemia-induced epigenetic patterns are considered a cent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Lara K, Maione, Anna G, Smith, Avi, Gerami-Naini, Behzad, Iyer, Lakshmanan K, Mooney, David J, Veves, Aristidis, Garlick, Jonathan A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622843/ https://www.ncbi.nlm.nih.gov/pubmed/25437049 http://dx.doi.org/10.4161/15592294.2014.967584

Ejemplares similares

Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration
por: Dinh, Thanh, et al.
Publicado: (2012)

Role of Endothelial Progenitor Cells and Inflammatory Cytokines in Healing of Diabetic Foot Ulcers
por: Tecilazich, Francesco, et al.
Publicado: (2013)

Single cell transcriptomic landscape of diabetic foot ulcers
por: Theocharidis, Georgios, et al.
Publicado: (2022)

Development and validation of a clinical prediction rule for development of diabetic foot ulceration: an analysis of data from five cohort studies
por: Chappell, Francesca M, et al.
Publicado: (2021)

Debridement of Diabetic Foot Ulcers
por: Dayya, David, et al.
Publicado: (2022)

Protocol for a systematic review and individual patient data meta-analysis of prognostic factors of foot ulceration in people with diabetes: the international research collaboration for the prediction of diabetic foot ulcerations (PODUS)
por: Crawford, Fay, et al.
Publicado: (2013)

Diabetes Treatment: Recent Developments
por: Veves, Aristidis, et al.
Publicado: (2013)

Fibroblast Growth Factor in Diabetic Foot Ulcer: Progress and Therapeutic Prospects
por: Liu, Ye, et al.
Publicado: (2021)

Diabetic Neuropathy: A cross-sectional study of the relationships among tests of neurophysiology
por: Gibbons, Christopher H., et al.
Publicado: (2010)

Foot Muscle Energy Reserves in Diabetic Patients Without and With Clinical Peripheral Neuropathy
por: Dinh, Thanh, et al.
Publicado: (2009)

Emergence of Fluconazole-resistant Candida Infections in Diabetic Foot Ulcers: Implications for Public Health
por: Arun, Chankramath S., et al.
Publicado: (2019)

Increased Population of CD40+ Fibroblasts Is Associated with Impaired Wound Healing and Chronic Inflammation in Diabetic Foot Ulcers
por: Littig, Joshua Patrick Bungalon, et al.
Publicado: (2022)

Perforating Ulcer of the Foot
por: Campbell, M. G.
Publicado: (1908)

DNA methylation analysis of negative pressure therapy effect in diabetic foot ulcers
por: Ludwig-Slomczynska, A H, et al.
Publicado: (2019)

Cold Exposure Exacerbates the Development of Diabetic Polyneuropathy in the Rat
por: Kasselman, Lora J., et al.
Publicado: (2009)

Increased Mortality in Diabetic Foot Ulcer Patients: The Significance of Ulcer Type
por: Chammas, N. K., et al.
Publicado: (2016)

Plantar Shear Stress in Individuals With a History of Diabetic Foot Ulcer: An Emerging Predictive Marker for Foot Ulceration
por: Yavuz, Metin, et al.
Publicado: (2017)

Republication of “The Evaluation and Treatment of Diabetic Foot Ulcers and Diabetic Foot Infections”
por: Del Core, Michael A., et al.
Publicado: (2023)

Epidermal growth factor effect on lipopolysaccharide-induced inflammation in fibroblasts derived from diabetic foot ulcer
por: Mendoza-Marí, Yssel, et al.
Publicado: (2022)

Single‐cell transcriptomics in human skin research: available technologies, technical considerations and disease applications
por: Theocharidis, Georgios, et al.
Publicado: (2022)

Genome-wide DNA Methylation in Treatment-naïve Ulcerative Colitis
por: Taman, Hagar, et al.
Publicado: (2018)

Fibroblasts Derived from Human Pluripotent Stem Cells Activate Angiogenic Responses In Vitro and In Vivo
por: Shamis, Yulia, et al.
Publicado: (2013)

Prevention of Diabetic Foot Ulcer
por: Iraj, Bijan, et al.
Publicado: (2013)

Management of Diabetic Foot Ulcers
por: Alexiadou, Kleopatra, et al.
Publicado: (2012)

Addressing Biomechanics Matters in Treating Diabetic Foot Ulcers
por: Wukich, Dane K.
Publicado: (2023)

Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin
por: Ramirez, Horacio A., et al.
Publicado: (2015)

A genome‐wide association study suggests that MAPK14 is associated with diabetic foot ulcers
por: Meng, W., et al.
Publicado: (2017)

Mortality Associated With Acute Charcot Foot and Neuropathic Foot Ulceration
por: van Baal, Juliette, et al.
Publicado: (2010)

Malignant Transformation in Diabetic Foot Ulcers—Case Reports and Review of the Literature
por: Dörr, Stefan, et al.
Publicado: (2019)

Neonatal corneal ulcer secondary to congenital entropion
por: Redd, Travis K., et al.
Publicado: (2022)

Mast Cells in Diabetes and Diabetic Wound Healing
por: Dong, Jie, et al.
Publicado: (2020)

Protocol for xenotransplantation of human skin and streptozotocin diabetes induction in immunodeficient mice to study impaired wound healing
por: Li, Zhuqing, et al.
Publicado: (2023)

Diabetic Foot Ulcer: Amputation on Request?
por: Collier, Andrew, et al.
Publicado: (2011)

Concordance in diabetic foot ulcer infection
por: Nelson, E Andrea, et al.
Publicado: (2013)

Role of Phenytoin in Diabetic Foot Ulcers
por: Bharathi Mohan, Padmalakshmi, et al.
Publicado: (2020)

Update on prevention of diabetic foot ulcer
por: Miranda, Cesare, et al.
Publicado: (2021)

Diabetic foot ulcer: Challenges and future
por: Yang, Li, et al.
Publicado: (2022)

Editorial: Pathogenesis of diabetic foot ulcers
por: Peng, Zhihong, et al.
Publicado: (2023)

Lower limb biomechanical characteristics of patients with neuropathic diabetic foot ulcers: the diabetes foot ulcer study protocol
por: Fernando, Malindu Eranga, et al.
Publicado: (2015)

Burden of diabetic foot ulcer in Nigeria: Current evidence from the multicenter evaluation of diabetic foot ulcer in Nigeria
por: Ugwu, Ejiofor, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_u92vrt0j5693mnhg5g04sqo1s0