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Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates

Fetal growth is determined by the feto-placental genome interacting with the maternal in utero environment. Failure of this interplay leads to poor placental development and fetal growth restriction (FGR), which is associated with future metabolic disease. We investigated whether whole genome methyl...

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Detalles Bibliográficos
Autores principales: Hillman, Sara L, Finer, Sarah, Smart, Melissa C, Mathews, Chris, Lowe, Robert, Rakyan, Vardhman K, Hitman, Graham A, Williams, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622857/
https://www.ncbi.nlm.nih.gov/pubmed/25496377
http://dx.doi.org/10.4161/15592294.2014.989741