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Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

The mechanisms by which intrinsically disordered proteins engage in rapid and highly selective binding is a subject of considerable interest and represents a central paradigm to nuclear pore complex (NPC) function, where nuclear transport receptors (NTRs) move through the NPC by binding disordered p...

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Detalles Bibliográficos
Autores principales: Milles, Sigrid, Mercadante, Davide, Aramburu, Iker Valle, Jensen, Malene Ringkjøbing, Banterle, Niccolò, Koehler, Christine, Tyagi, Swati, Clarke, Jane, Shammas, Sarah L., Blackledge, Martin, Gräter, Frauke, Lemke, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622936/
https://www.ncbi.nlm.nih.gov/pubmed/26456112
http://dx.doi.org/10.1016/j.cell.2015.09.047