MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin

It has been reported that persistent or excessive autophagy promotes cancer cell death during chemotherapy, either by enhancing the induction of apoptosis or mediating autophagic cell death. Here, we show that miR-15a and miR-16 are potent inducers of autophagy. Rictor, a component of mTORC2 complex...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Nunu, Wu, Jiangbin, Qiu, Wei, Lyu, Qing, He, Jie, Xie, Weidong, Xu, Naihan, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622988/
https://www.ncbi.nlm.nih.gov/pubmed/25945419
http://dx.doi.org/10.1080/15384047.2015.1040963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622988/
https://www.ncbi.nlm.nih.gov/pubmed/25945419
http://dx.doi.org/10.1080/15384047.2015.1040963

Ejemplares similares