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RNAi-mediated knockdown of INHBB increases apoptosis and inhibits steroidogenesis in mouse granulosa cells

Inhibins are members of the TGFβ superfamily and act as suppressors of follicle stimulating hormone (FSH) secretion from pituitary glands via a negative feedback mechanism to regulate folliculogenesis. In this study, the INHBB gene was knocked down by three RNAi-Ready pSIREN-RetroQ-ZsGreen vector- m...

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Detalles Bibliográficos
Autores principales: M’BAYE, Mohamed, HUA, Guohua, KHAN, Hamid Ali, YANG, Liguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623144/
https://www.ncbi.nlm.nih.gov/pubmed/26063610
http://dx.doi.org/10.1262/jrd.2014-158