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Pluripotent cell derivation from male germline cells by suppression of Dmrt1 and Trp53
Diploid germ cells are thought to have pluripotency potential. We recently described a method to derive pluripotent stem cells (PSCs) from cultured spermatogonial stem cells (SSCs) by depleting Trp53 and Dmrt1, both of which are known suppressors of teratomas. In this study, we used this technique t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Society for Reproduction and Development
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623154/ https://www.ncbi.nlm.nih.gov/pubmed/26227109 http://dx.doi.org/10.1262/jrd.2015-059 |