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Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix

BACKGROUND: There is significant evidence that severe tumor hypoxia may cause resistance to chemoradiotherapy and promote metastatic spread in locally advanced carcinoma of the uterine cervix. Some clinical investigations have suggested that high expression of hypoxia-inducible factor-1α (HIF-1α) an...

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Detalles Bibliográficos
Autores principales: Ellingsen, Christine, Andersen, Lise Mari K., Galappathi, Kanthi, Rofstad, Einar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623261/
https://www.ncbi.nlm.nih.gov/pubmed/26502718
http://dx.doi.org/10.1186/s12885-015-1828-2