Cargando…

Functionalized micro-capillary film for the rapid at-line analysis of IgG aggregates in a cell culture bioreactor

A micro-capillary film has been developed that offers the potential for an at-line analytical tool for rapid aggregate analysis during biopharmaceutical antibody production. A non-porous walled micro-capillary film (NMCF) with cation exchange functionality was demonstrated to act as a chromatography...

Descripción completa

Detalles Bibliográficos
Autores principales: Townsend, Matthew J, Gruber, David E, Kuiper, Marcel, Lazar, Radu A, Field, Ray P, Turner, Richard E, Slater, Nigel KH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623336/
https://www.ncbi.nlm.nih.gov/pubmed/26176737
http://dx.doi.org/10.1080/19420862.2015.1065365