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Functionalized micro-capillary film for the rapid at-line analysis of IgG aggregates in a cell culture bioreactor
A micro-capillary film has been developed that offers the potential for an at-line analytical tool for rapid aggregate analysis during biopharmaceutical antibody production. A non-porous walled micro-capillary film (NMCF) with cation exchange functionality was demonstrated to act as a chromatography...
Autores principales: | Townsend, Matthew J, Gruber, David E, Kuiper, Marcel, Lazar, Radu A, Field, Ray P, Turner, Richard E, Slater, Nigel KH |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623336/ https://www.ncbi.nlm.nih.gov/pubmed/26176737 http://dx.doi.org/10.1080/19420862.2015.1065365 |
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