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Delayed-release prednisone improves fatigue and health-related quality of life: findings from the CAPRA-2 double-blind randomised study in rheumatoid arthritis

OBJECTIVES: Like morning stiffness, fatigue is a common, debilitating symptom of rheumatoid arthritis (RA). Delayed-release (DR) prednisone is designed for evening administration (approximately 22:00) and releases 4 h later to coincide with the rise of nocturnal inflammatory cytokines associated wit...

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Detalles Bibliográficos
Autores principales: Alten, Rieke, Grahn, Amy, Holt, Robert J, Rice, Patricia, Buttgereit, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623361/
https://www.ncbi.nlm.nih.gov/pubmed/26535146
http://dx.doi.org/10.1136/rmdopen-2015-000134