VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage

All types of DNA damage cause a local alteration and relaxation of chromatin structure. Sensing and reacting to this initial chromatin alteration is a necessary trigger for any type of DNA damage response (DDR). In this context, chromatin kinases are likely candidates to participate in detection and...

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Detalles Bibliográficos
Autores principales: Salzano, Marcella, Sanz-García, Marta, Monsalve, Diana M, Moura, David S, Lazo, Pedro A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623420/
https://www.ncbi.nlm.nih.gov/pubmed/25923214
http://dx.doi.org/10.1080/15592294.2015.1028708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623420/
https://www.ncbi.nlm.nih.gov/pubmed/25923214
http://dx.doi.org/10.1080/15592294.2015.1028708

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