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Choroidal neovascularization is inhibited via an intraocular decrease of inflammatory cells in mice lacking complement component C3
In early age-related macular degeneration (AMD), complement component C3 can be observed in drusen, which is the accumulation of material beneath the retinal pigment epithelium. The complement pathways, via the activation of C3, can upregulate the expression of cytokines and their receptors and the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623476/ https://www.ncbi.nlm.nih.gov/pubmed/26507897 http://dx.doi.org/10.1038/srep15702 |