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Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages

Glioblastoma cells produce and release high amounts of glutamate into the extracellular milieu and subsequently can trigger seizure in patients. Tumor-associated microglia/macrophages (TAMs), consisting of both parenchymal microglia and monocytes-derived macrophages (MDMs) recruited from the blood,...

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Detalles Bibliográficos
Autores principales: Choi, Judy, Stradmann-Bellinghausen, Beate, Yakubov, Eduard, Savaskan, Nicolai E, Régnier-Vigouroux, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623498/
https://www.ncbi.nlm.nih.gov/pubmed/26047211
http://dx.doi.org/10.1080/15384047.2015.1056406