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α-Melanocyte-stimulating hormone prevents glutamate excitotoxicity in developing chicken retina via MC4R-mediated down-regulation of microRNA-194

Glutamate excitotoxicity is a common pathology to blinding ischemic retinopathies, such as diabetic retinopathy, glaucoma, and central retinal vein or artery occlusion. The development of an effective interventional modality to glutamate excitotoxicity is hence important to preventing blindness. Her...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Bo, Qiyu, Wu, Weihui, Xu, Chang, Yu, Guangwei, Ma, Shan, Yang, Qianhui, Cao, Yunshan, Han, Qian, Ru, Yusha, Liu, Xun, Hua Wei, Rui, Wang, Fei E., Zhang, Xiaomin, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623527/
https://www.ncbi.nlm.nih.gov/pubmed/26507936
http://dx.doi.org/10.1038/srep15812