Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1)

Disordered proteins are highly prevalent in biological systems, they control myriad signaling and regulatory processes, and their levels and/or cellular localization are often altered in human disease. In contrast to folded proteins, disordered proteins, due to conformational heterogeneity and dynam...

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Detalles Bibliográficos
Autores principales: Iconaru, Luigi I., Ban, David, Bharatham, Kavitha, Ramanathan, Arvind, Zhang, Weixing, Shelat, Anang A., Zuo, Jian, Kriwacki, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623604/
https://www.ncbi.nlm.nih.gov/pubmed/26507530
http://dx.doi.org/10.1038/srep15686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623604/
https://www.ncbi.nlm.nih.gov/pubmed/26507530
http://dx.doi.org/10.1038/srep15686

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