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Quantitative structure–activity relationship study of P2X(7) receptor inhibitors using combination of principal component analysis and artificial intelligence methods
P2X(7) antagonist activity for a set of 49 molecules of the P2X(7) receptor antagonists, derivatives of purine, was modeled with the aid of chemometric and artificial intelligence techniques. The activity of these compounds was estimated by means of combination of principal component analysis (PCA),...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623620/ https://www.ncbi.nlm.nih.gov/pubmed/26600858 |