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Evaluation of regulatory genetic variants in POU5F1 and risk of congenital heart disease in Han Chinese

OCT4 is a transcription factor of the POU family, which plays a key role in embryonic development and stem cell pluripotency. Previous studies have shown that Oct4 is required for cardiomyocyte differentiation in mice and its depletion could result in cardiac morphogenesis in embryo. However, whethe...

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Detalles Bibliográficos
Autores principales: Lin, Yuan, Ding, Chenyue, Zhang, Kai, Ni, Bixian, Da, Min, Hu, Liang, Hu, Yuanli, Xu, Jing, Wang, Xiaowei, Chen, Yijiang, Mo, Xuming, Cui, Yugui, Shen, Hongbing, Sha, Jiahao, Liu, Jiayin, Hu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623744/
https://www.ncbi.nlm.nih.gov/pubmed/26507003
http://dx.doi.org/10.1038/srep15860