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Evaluation of regulatory genetic variants in POU5F1 and risk of congenital heart disease in Han Chinese
OCT4 is a transcription factor of the POU family, which plays a key role in embryonic development and stem cell pluripotency. Previous studies have shown that Oct4 is required for cardiomyocyte differentiation in mice and its depletion could result in cardiac morphogenesis in embryo. However, whethe...
Autores principales: | Lin, Yuan, Ding, Chenyue, Zhang, Kai, Ni, Bixian, Da, Min, Hu, Liang, Hu, Yuanli, Xu, Jing, Wang, Xiaowei, Chen, Yijiang, Mo, Xuming, Cui, Yugui, Shen, Hongbing, Sha, Jiahao, Liu, Jiayin, Hu, Zhibin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623744/ https://www.ncbi.nlm.nih.gov/pubmed/26507003 http://dx.doi.org/10.1038/srep15860 |
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