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Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1

BACKGROUND: Completion of HIV life cycle in CD4(+) T lymphocytes needs cell activation. We recently reported that treatment of resting CD4(+) T lymphocytes with exosomes produced by HIV-1 infected cells induces cell activation and susceptibility to HIV replication. Here, we present data regarding th...

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Detalles Bibliográficos
Autores principales: Arenaccio, Claudia, Anticoli, Simona, Manfredi, Francesco, Chiozzini, Chiara, Olivetta, Eleonora, Federico, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623921/
https://www.ncbi.nlm.nih.gov/pubmed/26502902
http://dx.doi.org/10.1186/s12977-015-0216-y