Cargando…

Comparing the Assembly and Handedness Dynamics of (H3.3-H4)(2) Tetrasomes to Canonical Tetrasomes

Eukaryotic nucleosomes consists of an (H3-H4)(2) tetramer and two H2A-H2B dimers, around which 147 bp of DNA are wrapped in 1.7 left-handed helical turns. During chromatin assembly, the (H3-H4)(2) tetramer binds first, forming a tetrasome that likely constitutes an important intermediate during ongo...

Descripción completa

Detalles Bibliográficos
Autores principales: Vlijm, Rifka, Lee, Mina, Ordu, Orkide, Boltengagen, Anastasiya, Lusser, Alexandra, Dekker, Nynke H., Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623960/
https://www.ncbi.nlm.nih.gov/pubmed/26506534
http://dx.doi.org/10.1371/journal.pone.0141267