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Comparing the Assembly and Handedness Dynamics of (H3.3-H4)(2) Tetrasomes to Canonical Tetrasomes
Eukaryotic nucleosomes consists of an (H3-H4)(2) tetramer and two H2A-H2B dimers, around which 147 bp of DNA are wrapped in 1.7 left-handed helical turns. During chromatin assembly, the (H3-H4)(2) tetramer binds first, forming a tetrasome that likely constitutes an important intermediate during ongo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623960/ https://www.ncbi.nlm.nih.gov/pubmed/26506534 http://dx.doi.org/10.1371/journal.pone.0141267 |