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DynaFace: Discrimination between Obligatory and Non-obligatory Protein-Protein Interactions Based on the Complex’s Dynamics

Protein-protein interfaces have been evolutionarily-designed to enable transduction between the interacting proteins. Thus, we hypothesize that analysis of the dynamics of the complex can reveal details about the nature of the interaction, and in particular whether it is obligatory, i.e., persists t...

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Detalles Bibliográficos
Autores principales: Soner, Seren, Ozbek, Pemra, Garzon, Jose Ignacio, Ben-Tal, Nir, Haliloglu, Turkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623975/
https://www.ncbi.nlm.nih.gov/pubmed/26506003
http://dx.doi.org/10.1371/journal.pcbi.1004461