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Peptidoglycan Up-Regulates CXCL8 Expression via Multiple Pathways in Monocytes/Macrophages

Peptidoglycan (PG), the gram positive bacterial pathogen-associated molecular patterns (PAMP), is detected in a high proportion in macrophage-rich atheromatous regions, and expression of chemokine CXCL8, which triggers monocyte arrest on early atherosclerotic endothelium, is elevated in monocytes/ma...

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Detalles Bibliográficos
Autores principales: Lee, Chung Won, Chung, Sung Woon, Bae, Mi Ju, Song, Seunghwan, Kim, Sang-pil, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624073/
https://www.ncbi.nlm.nih.gov/pubmed/26535082
http://dx.doi.org/10.4062/biomolther.2015.053